Dendritic-tumor fusion cells derived heat shock protein70-peptide complex has enhanced immunogenicity.

Tumor-derived heat shock protein70-peptide complexes (HSP70.PC-Tu) have shown great promise in tumor immunotherapy due to numerous advantages. However, large-scale phase III clinical trials showed that the limited immunogenicity remained to be enhanced. In previous research, we demonstrated that hea...

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Bibliographic Details
Main Authors: Yunfei Zhang, Yong Zhang, Jun Chen, Yunyan Liu, Wen Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427282?pdf=render