Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.

Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.

BACKGROUND:The prevalence of BRCA1/2 variants in Chinese breast cancer patients varies among studies. Germline or somatic BRCA1/2 mutations are associated with sensitivity to poly(ADP-ribose) polymerase-1 inhibitors and DNA-damaging agents. We aimed to investigate the distribution of both somatic an...

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Bibliographic Details
Main Authors: Xiaorong Zhong, Zhengwei Dong, Hua Dong, Jiayuan Li, Zuxiang Peng, Ling Deng, Xuehua Zhu, Yun Sun, Xuesong Lu, Fuxiao Shen, Xinying Su, Liying Zhang, Yi Gu, Hong Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892623?pdf=render

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http://europepmc.org/articles/PMC4892623?pdf=render

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