Detection of TP53 R249 Mutation in Iranian Patients with Pancreatic Cancer
The TP53 gene encodes tumor protein p53 which play a major role in the etiology of pancreatic cancer. The important role of codon 249 of TP53 for binding of p53 to its sequence-specific consensus site in DNA has been revealed by crystallography’s studies, and mutation at this codon was detected in t...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Journal of Oncology |
Online Access: | http://dx.doi.org/10.1155/2013/738915 |