Piperine synergistically enhances the effect of temozolomide against temozolomide-resistant human glioma cell lines

Temozolomide (TMZ) is an alkylating chemotherapy agent used in the clinical treatment of glioblastoma multiforme (GBM) patients. Piperine (PIP) is a naturally occurring pungent nitrogenous substance present in the fruits of peppers. We investigated the anti-cancer efficacies of PIP alone and in comb...

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Bibliographic Details
Main Authors: Somi Jeong, Seunghwa Jung, Gyun-Seok Park, Juhyun Shin, Jae-Wook Oh
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Bioengineered
Subjects:
Online Access:http://dx.doi.org/10.1080/21655979.2020.1794100