Tumor infiltrating CD8+ and Foxp3+ lymphocytes correlate to clinical outcome and human papillomavirus (HPV) status in tonsillar cancer.

Tumor infiltrating CD8+ and Foxp3+ lymphocytes correlate to clinical outcome and human papillomavirus (HPV) status in tonsillar cancer.

BACKGROUND: Human papillomavirus (HPV) is a causative factor for tonsillar squamous cell carcinoma (TSCC) and patients with HPV positive (HPV(+)) TSCC have a better clinical outcome than those with HPV negative (HPV(-)) TSCC. However, since not all patients with HPV(+) TSCC respond to treatment, add...

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Bibliographic Details
Main Authors: Anders Näsman, Mircea Romanitan, Cecilia Nordfors, Nathalie Grün, Hemming Johansson, Lalle Hammarstedt, Linda Marklund, Eva Munck-Wikland, Tina Dalianis, Torbjörn Ramqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3373553?pdf=render

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http://europepmc.org/articles/PMC3373553?pdf=render

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