Enhanced T Cell Responses Induced by a Necrotic Dendritic Cell Vaccine, Expressing HCV NS3

Enhanced T Cell Responses Induced by a Necrotic Dendritic Cell Vaccine, Expressing HCV NS3

A vaccine that induces potent, broad and sustained cell-mediated immunity, resulting in effective memory has the potential to restrict hepatitis C (HCV) virus infection. Early, multi-functional CD4+ and CD8+ T cell responses against non-structural protein 3 (NS3) have been associated with HCV cleara...

Full description

Bibliographic Details
Main Authors: Zelalem A. Mekonnen, Makutiro G. Masavuli, Wenbo Yu, Jason Gummow, Dawn M. Whelan, Zahraa Al-Delfi, Joseph Torresi, Eric J. Gowans, Branka Grubor-Bauk
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
necrosis
HCV
cell mediated immunity
cross presentation
vaccine
hepatitis (C) virus
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.559105/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.559105/full

Similar Items