The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma

The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma

The oncological role of the density of nerve fibers (NFs) in the tumor microenvironment (TME) in intrahepatic cholangiocarcinoma (iCCA) remains to be determined. Therefore, data of 95 iCCA patients who underwent hepatectomy between 2010 and 2019 was analyzed regarding NFs and long-term outcome. Exte...

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Bibliographic Details
Main Authors: Jan Bednarsch, Xiuxiang Tan, Zoltan Czigany, Dong Liu, Sven Arke Lang, Shivan Sivakumar, Jakob Nikolas Kather, Simone Appinger, Mika Rosin, Shiva Boroojerdi, Edgar Dahl, Nadine Therese Gaisa, Marcel den Dulk, Mariëlle Coolsen, Tom Florian Ulmer, Ulf Peter Neumann, Lara Rosaline Heij
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
intrahepatic cholangiocarcinoma
nerve fibers
tumor microenvironment
oncological outcome
biomarker
Online Access:https://www.mdpi.com/2072-6694/13/15/3661

Internet

https://www.mdpi.com/2072-6694/13/15/3661

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