APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.

APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.

Myeloid cells play numerous roles in HIV-1 pathogenesis serving as a vehicle for viral spread and as a viral reservoir. Yet, cells of this lineage generally resist HIV-1 infection when compared to cells of other lineages, a phenomenon particularly acute during the early phases of infection. Here, we...

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Bibliographic Details
Main Authors: Gregory Berger, Stéphanie Durand, Guillaume Fargier, Xuan-Nhi Nguyen, Stéphanie Cordeil, Serge Bouaziz, Delphine Muriaux, Jean-Luc Darlix, Andrea Cimarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3178557?pdf=render

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http://europepmc.org/articles/PMC3178557?pdf=render

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