Sustained Release of MiR-217 Inhibitor by Nanoparticles Facilitates MSC-Mediated Attenuation of Neointimal Hyperplasia After Vascular Injury

Sustained Release of MiR-217 Inhibitor by Nanoparticles Facilitates MSC-Mediated Attenuation of Neointimal Hyperplasia After Vascular Injury

Mesenchymal stem cells (MSCs) have been proven capable of differentiating into endothelial cells (ECs) and increasing vascular density in mouse ischemia models. However, the therapeutic potential of MSCs in neointimal hyperplasia after vascular injury is still not fully understood. In this study, we...

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Bibliographic Details
Main Authors: Hong Yu, Yutao Hua, Yecheng He, Yin Wang, Xingjian Hu, Si Chen, Junwei Liu, Junjie Yang, Huadong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
mesenchymal stem cells
atherosclerosis
miR-217
PLGA nanoparticle
vascular injury
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.739107/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.739107/full

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