Short Exposure to Ethanol Diminishes Caspase-1 and ASC Activation in Human HepG2 Cells In Vitro

Short Exposure to Ethanol Diminishes Caspase-1 and ASC Activation in Human HepG2 Cells In Vitro

This paper discusses how the assembly of pro-caspase-1 and apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) in macromolecular protein complexes, inflammasomes, activates caspase-1. The present study investigates the molecular mechanisms of inflammasome activation...

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Bibliographic Details
Main Authors: Jason-Alexander Hörauf, Shinwan Kany, Andrea Janicova, Baolin Xu, Teodora Vrdoljak, Ramona Sturm, Ildiko Rita Dunay, Lukas Martin, Borna Relja
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
inflammation
inflammasome
caspase-1
alcohol
liver
in vitro
Online Access:https://www.mdpi.com/1422-0067/21/9/3196

Internet

https://www.mdpi.com/1422-0067/21/9/3196

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