Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons

<p>Abstract</p> <p>Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pa...

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Bibliographic Details
Main Authors: Hoe Hyang-Sook, Freeman Jacob, Rebeck G William
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/1/1/18