M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade

M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade

Abstract Background Transfer of noncoding microRNAs (miRNAs) by extracellular vesicles (EVs) promotes the development of chemoresistance in many tumor types. Additionally, restoration or depletion of several miRNAs has been observed in multiple cancer types including gastric cancer (GC). In this pre...

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Bibliographic Details
Main Authors: Yu Zhang, Wenbo Meng, Ping Yue, Xun Li
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Gastric cancer
microRNA-130b-3p
M2 macrophages
Extracellular vesicles
MLL3
GRHL2
Online Access:http://link.springer.com/article/10.1186/s13046-020-01626-7

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http://link.springer.com/article/10.1186/s13046-020-01626-7

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