Design, ecofriendly synthesis, anticancer and antimicrobial screening of innovative Biginelli dihydropyrimidines using β-aroylpyruvates as synthons

New ecofriendly Biginelli reaction procedures have been adapted to prepare new dihydropyrimidines (DHPMs) using a multicomponent one-pot reaction. All the synthesized compounds were evaluated for their anticancer activity against 59 human cancer cell lines and evaluated for their antimicrobial activ...

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Bibliographic Details
Main Authors: Afaf El-Malah, Zeinab Mahmoud, Heba Hamed Salem, Amr M. Abdou, Mona M. H. Soliman, Rasha A. Hassan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-04-01
Series:Green Chemistry Letters and Reviews
Subjects:
Online Access:http://dx.doi.org/10.1080/17518253.2021.1896789