Inhalation of specific anti-Pseudomonas aeruginosa IgY antibodies transiently decreases P. aeruginosa colonization of the airway in mechanically ventilated piglets

Abstract Background P. aeruginosa is a pathogen frequently resistant to antibiotics and a common cause of ventilator-associated pneumonia (VAP). Non-antibiotic strategies to prevent or treat VAP are therefore of major interest. Specific polyclonal avian IgY antibodies have previously been shown to b...

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Bibliographic Details
Main Authors: A. Otterbeck, K. Hanslin, E. Lidberg Lantz, A. Larsson, J. Stålberg, M. Lipcsey
Format: Article
Language:English
Published: SpringerOpen 2019-04-01
Series:Intensive Care Medicine Experimental
Subjects:
VAP
HAP
Online Access:http://link.springer.com/article/10.1186/s40635-019-0246-1