GAP-43 and BASP1 in Axon Regeneration: Implications for the Treatment of Neurodegenerative Diseases

GAP-43 and BASP1 in Axon Regeneration: Implications for the Treatment of Neurodegenerative Diseases

Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal growth, regeneration, and plasticity. These functions highly depend on changes in GAP-43 and BASP1 expression levels a...

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Bibliographic Details
Main Authors: Daayun Chung, Andrew Shum, Gabriela Caraveo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GAP-43
BASP1
phosphorylation
neural injury response
axon regeneration
neurodegenerative diseases
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.567537/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.567537/full

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