Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host

Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host

Dual RNA sequencing (RNA-seq) offers the promise of determining an interactome at a transcriptional level between a bacterium and the host but has yet to be done on any bacterial infection in human tissue. We performed dual RNA-seq and metabolomics analyses on wounded and infected sites following ex...

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Bibliographic Details
Main Authors: Brad Griesenauer, Tuan M. Tran, Kate R. Fortney, Diane M. Janowicz, Paula Johnson, Hongyu Gao, Stephen Barnes, Landon S. Wilson, Yunlong Liu, Stanley M. Spinola
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
dual RNA-seq
Haemophilus ducreyi
human infection model
interactome
metabolome
Online Access:https://doi.org/10.1128/mBio.01193-19

Internet

https://doi.org/10.1128/mBio.01193-19

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