Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis

Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis

Evidence indicates an intimate connection between the neuroendocrine and the immune systems. A number of in vitro and in vivo studies have demonstrated growth hormone (GH) involvement in immune regulation. The GH receptor is expressed by several leukocyte subpopulations, and GH modulates immune cell...

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Bibliographic Details
Main Authors: Ricardo Villares, Gabriel Criado, Yasmina Juarranz, Mercedes Lopez-Santalla, Eva M. García-Cuesta, José M. Rodríguez-Frade, Javier Leceta, Pilar Lucas, José Luis Pablos, Carlos Martínez-A, Marina I. Garin, Rosa P. Gomariz, Mario Mellado
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
collagen-induced arthritis
growth hormone
Th17/Th1 cells
cytokines
immune regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01165/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01165/full

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