Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathway

The successful treatment of keloids is a great challenge in the plastic surgery field. Activating transcription factor 3 (ATF3) is discovered as an adaptive responsive gene, which plays a critical role in fibroblast activation. This study aimed to investigate the expression and biological role of AT...

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Bibliographic Details
Main Authors: Xue-Ming Wang, Xiu-Mei Liu, Yuting Wang, Zhen-Yu Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
keloid
proliferation
invasion
activating transcription factor 3
Online Access:http://dx.doi.org/10.1080/21655979.2020.1860491

Internet

http://dx.doi.org/10.1080/21655979.2020.1860491

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