Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal metabolic incorporation of the sialic acid an...

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Bibliographic Details
Main Authors: Arne Homann, Riaz-ul Qamar, Sevnur Serim, Petra Dersch, Jürgen Seibel
Format: Article
Language:English
Published: Beilstein-Institut 2010-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.6.24