Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates.

Genetic variants modulating CRIPTO serum levels identified by genome-wide association study in Cilento isolates.

Cripto, the founding member of the EGF-CFC genes, plays an essential role in embryo development and is involved in cancer progression. Cripto is a GPI-anchored protein that can interact with various components of multiple signaling pathways, such as TGF-β, Wnt and MAPK, driving different processes,...

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Main Authors: Daniela Ruggiero, Stefania Nappo, Teresa Nutile, Rossella Sorice, Francesco Talotta, Emilia Giorgio, Celine Bellenguez, Anne-Louise Leutenegger, Giovanna L Liguori, Marina Ciullo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4309561?pdf=render

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http://europepmc.org/articles/PMC4309561?pdf=render

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