Umbelliferone Ameliorates Benign Prostatic Hyperplasia by Inhibiting Cell Proliferation and G1/S Phase Cell Cycle Progression through Regulation of STAT3/E2F1 Axis

Umbelliferone Ameliorates Benign Prostatic Hyperplasia by Inhibiting Cell Proliferation and G1/S Phase Cell Cycle Progression through Regulation of STAT3/E2F1 Axis

Umbelliferone (UMB), also known as 7-hydroxycoumarin, is a derivative of coumarin, which is widely found in many plants such as carrots, coriander, and garden angelica. Although many studies have already revealed the various pharmacological properties of UMB, its effect on benign prostatic hyperplas...

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Bibliographic Details
Main Authors: Hyo-Jung Kim, Bo-Ram Jin, Hyo-Jin An
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
androgen receptor
benign prostatic hyperplasia
E2F transcription factor 1
signal transducer and activator of transcription 3
testosterone propionate
umbelliferone
Online Access:https://www.mdpi.com/1422-0067/22/16/9019

Internet

https://www.mdpi.com/1422-0067/22/16/9019

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