A Plasmodium falciparum protein tyrosine phosphatase inhibitor identified from the ChEMBL‐NTD database blocks parasite growth

A Plasmodium falciparum protein tyrosine phosphatase inhibitor identified from the ChEMBL‐NTD database blocks parasite growth

Post‐translational modifications, especially reversible phosphorylation, are among the most common mechanisms that regulate protein function and biological processes in Plasmodium species. Of the Plasmodium phosphatases, phosphatase of regenerating liver (PfPRL) is secreted and is an essential phosp...

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Bibliographic Details
Main Authors: Rajan Pandey, Priya Gupta, Asif Mohmmed, Pawan Malhotra, Dinesh Gupta
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:FEBS Open Bio
Subjects:
enzymatic assay
inhibition assay
phosphatase
plasmodium
post‐translational modifications
Online Access:https://doi.org/10.1002/2211-5463.13171

Internet

https://doi.org/10.1002/2211-5463.13171

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