Mitochondrial haplogroups and polymorphisms reveal no association with sporadic prostate cancer in a southern European population.

BACKGROUND: It is known that mitochondria play an important role in certain cancers (prostate, renal, breast, or colorectal) and coronary disease. These organelles play an essential role in apoptosis and the production of reactive oxygen species; in addition, mtDNA also reveals the history of popula...

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Bibliographic Details
Main Authors: María Jesús Álvarez-Cubero, María Saiz Guinaldo, Luís Javier Martínez-González, Juan Carlos Álvarez Merino, José Manuel Cózar Olmo, José Antonio Lorente Acosta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398884?pdf=render