Combined 2D-QSAR, Principal Component Analysis and Sensitivity Analysis Studies on Fluoroquinolones’ Genotoxicity

In this paper, two-dimensional quantitative structure−activity relationship (2D-QSAR) and principal component analysis (PCA) methods were employed to screen the main parameters affecting the genotoxicity of fluoroquinolones (FQs), and the rules affecting the genetic toxicity of FQs were in...

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Bibliographic Details
Main Authors: Meijin Du, Dan Zhang, Yilin Hou, Xiaohui Zhao, Yu Li
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:https://www.mdpi.com/1660-4601/16/21/4156