Genomic and Transcriptomic Characterization of Relapsed SCLC Through Rapid Research Autopsy

Genomic and Transcriptomic Characterization of Relapsed SCLC Through Rapid Research Autopsy

Introduction: Relapsed SCLC is characterized by therapeutic resistance and high mortality rate. Despite decades of research, mechanisms responsible for therapeutic resistance have remained elusive owing to limited tissues available for molecular studies. Thus, an unmet need remains for molecular cha...

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Bibliographic Details
Main Authors: Hui-Zi Chen, MD, PhD, Russell Bonneville, BS, Anoosha Paruchuri, PhD, Julie W. Reeser, PhD, Michele R. Wing, PhD, Eric Samorodnitsky, PhD, Melanie A. Krook, PhD, Amy M. Smith, BS, Thuy Dao, BS, Jharna Miya, MS, Walter Wang, BS, Lianbo Yu, PhD, Aharon G. Freud, MD, PhD, Patricia Allenby, MD, Sharon Cole, MD, Gregory Otterson, MD, Peter Shields, MD, David P. Carbone, MD, PhD, Sameek Roychowdhury, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:JTO Clinical and Research Reports
Subjects:
Small cell lung cancer
Research autopsy
Tumor heterogeneity
Treatment resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2666364321000230

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http://www.sciencedirect.com/science/article/pii/S2666364321000230

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