Top-Down Synthesis of a Lamivudine-Zidovudine Nano Co-Crystal

Lamivudine (3TC) and zidovudine (AZT) are antiretroviral agents used to manage HIV/AIDS infection. A wet media milling top-down approach was used to develop and produce nano co-crystals of 3TC and AZT. Micro co-crystals were prepared by solvent evaporation and subsequently milled in the presence of...

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Bibliographic Details
Main Authors: Bwalya A. Witika, Vincent J. Smith, Roderick B. Walker
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/11/1/33