Exploring the Mechanism of Total Flavonoids of Drynariae Rhizoma to Improve Large Bone Defects by Network Pharmacology and Experimental Assessment

Exploring the Mechanism of Total Flavonoids of Drynariae Rhizoma to Improve Large Bone Defects by Network Pharmacology and Experimental Assessment

Drynariae Rhizoma (DR) has been demonstrated to be effective in promoting fracture healing in clinical use. In the study, we tried to predicate potential signaling pathways and active ingredients of DR via network pharmacology, uncover its regulation mechanism to improve large bone defects by in viv...

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Bibliographic Details
Main Authors: Weipeng Sun, Minying Li, Lei Xie, Zhexing Mai, Yan Zhang, Lieliang Luo, Zijian Yan, Zige Li, Hang Dong, Feng Huang, Zhen Shen, Ziwei Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
drynariae rhizoma
experimental assessment
gusuibu
large bone defects
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.603734/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.603734/full

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