Oxidative stress and cell damage in a model of precancerous lesions and advanced hepatocellular carcinoma in rats

Oxidative stress and cell damage in a model of precancerous lesions and advanced hepatocellular carcinoma in rats

Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer deaths throughout the world. This study was aimed to analyze oxidative stress and cell damage in a multistage model of liver carcinogenesis induced by diethylnitrosamine (DEN) in rats. Male Wistar rats weighing 145–150 g were...

Full description

Bibliographic Details
Main Authors: Andrea J. Moreira, Graziella Rodrigues, Silvia Bona, Carlos Thadeu Cerski, Claudio A. Marroni, Jose L. Mauriz, Javier González-Gallego, Norma P. Marroni
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Hepatocarcinoma
Diethylnitrosamine
Oxidative stress
Nuclear factor erythroid 2-related factor 2
Nitric oxide synthase
Heat shock protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014001504

Internet

http://www.sciencedirect.com/science/article/pii/S2214750014001504

Similar Items