Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin

<p>Abstract</p> <p>Background</p> <p>Colon cancer stem cells may drive carcinogenesis and account for chemotherapeutic failure. Although many markers for these cells have been proposed, there is no complete agreement regarding them, nor has their presence in the early p...

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Bibliographic Details
Main Authors: Femia Angelo Pietro, Dolara Piero, Salvadori Maddalena, Caderni Giovanna
Format: Article
Language:English
Published: BMC 2013-02-01
Series:BMC Cancer
Subjects:
Online Access:http://www.biomedcentral.com/1471-2407/13/48