Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.

Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.

Hematopoietic stem cells (HSC) are rare, multipotent cells capable of generating all specialized cells of the blood system. Appropriate regulation of HSC quiescence is thought to be crucial to maintain their lifelong function; however, the molecular pathways controlling stem cell quiescence remain p...

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Bibliographic Details
Main Authors: E Camilla Forsberg, Emmanuelle Passegué, Susan S Prohaska, Amy J Wagers, Martina Koeva, Joshua M Stuart, Irving L Weissman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2808351?pdf=render

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http://europepmc.org/articles/PMC2808351?pdf=render

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