Pathomechanism of atopic dermatitis in the perspective of T cell subsets and skin barrier functions – “Which comes first, the chicken or the egg?”

Atopic dermatitis (AD) is a common skin condition that is characterized by a complex, heterogeneous pathogenesis. The possible candidates for its pathogenesis include skin barrier abnormality and allergy/immunology aspects. It has long been asked, “Which comes first, the barrier dysfunction or the a...

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Bibliographic Details
Main Author: Kenji Kabashima
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-12-01
Series:Dermatologica Sinica
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S102781171200078X