Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma.

Salivary gland adenoid cystic carcinoma (ACC) is a rare cancer, accounting for only 1% of all head and neck malignancies. ACC is well known for perineural invasion and distant metastasis, but its underlying molecular mechanisms of carcinogenesis are still unclear.Here, we show that a novel oncogenic...

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Bibliographic Details
Main Authors: Chunbo Shao, Marietta Tan, Justin A Bishop, Jia Liu, Weiliang Bai, Daria A Gaykalova, Takenori Ogawa, Ami R Vikani, Yuri Agrawal, Ryan J Li, Myoung Sook Kim, William H Westra, David Sidransky, Joseph A Califano, Patrick K Ha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492451?pdf=render