Transcriptional and genomic mayhem due to aging-induced nucleosome loss in budding yeast

Transcriptional and genomic mayhem due to aging-induced nucleosome loss in budding yeast

All eukaryotic genomes are assembled into a nucleoprotein structure termed chromatin, which is comprised of regular arrays of nucleosomes. Each nucleosome consists of eight core histone protein molecules around which the DNA is wrapped 1.75 times. The ultimate consequence of packaging the genome int...

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Bibliographic Details
Main Authors: Zheng Hu, Kaifu Chen, Wei Li, Jessica K. Tyler
Format: Article
Language:English
Published: Shared Science Publishers OG 2014-04-01
Series:Microbial Cell
Subjects:
DNA damage
translocation
transcription
histones
yeast
aging
Online Access:http://microbialcell.com/researcharticles/transcriptional-and-genomic-mayhem-due-to-aging-induced-nucleosome-loss-in-budding-yeast/

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http://microbialcell.com/researcharticles/transcriptional-and-genomic-mayhem-due-to-aging-induced-nucleosome-loss-in-budding-yeast/

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