Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4

<p>Abstract</p> <p>Background</p> <p>The cellular response of malignant tumors to hypoxia is diverse. Several important endogenous metabolic markers are upregulated under hypoxic conditions. We examined the staining patterns and co-expression of HIF-1α, CAIX, LDH-5, GLU...

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Bibliographic Details
Main Authors: Bussink Johan, van der Kogel Albert J, Lok Jasper, Rademakers Saskia E, Kaanders Johannes HAM
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/167