Inosine as a Tool to Understand and Treat Central Nervous System Disorders: A Neglected Actor?

Since the 1970s, when ATP was identified as a co-transmitter in sympathetic and parasympathetic nerves, it and its active metabolite adenosine have been considered relevant signaling molecules in biological and pathological processes in the central nervous system (CNS). Meanwhile, inosine, a natural...

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Bibliographic Details
Main Authors: Francisney Pinto Nascimento, Sérgio José Macedo-Júnior, Fernanda Rocha Lapa-Costa, Fernando Cezar-dos-Santos, Adair R. S. Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.703783/full