Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease

Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson’s disease

Abstract Parkinson’s disease (PD) patients often suffer from non-motor symptoms like sleep dysregulation, mood disturbances or circadian rhythms dysfunction. The melanopsin-containing retinal ganglion cells are involved in the control and regulation of these processes and may be affected in PD, as o...

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Bibliographic Details
Main Authors: Isabel Ortuño-Lizarán, Gema Esquiva, Thomas G. Beach, Geidy E. Serrano, Charles H. Adler, Pedro Lax, Nicolás Cuenca
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Acta Neuropathologica Communications
Subjects:
Retina
Parkinson’s disease
Circadian rhythms
Sleep disorders
Melanopsin retinal ganglion cell
Human
Online Access:http://link.springer.com/article/10.1186/s40478-018-0596-z

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http://link.springer.com/article/10.1186/s40478-018-0596-z

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