Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages

Shape transformation of proteins created by design in the laboratory is challenging. Here, the authors present a disulfide-mediated approach for the preparation of 16-mer, 24-mer, and 48-mer nanocages from an 8-mer bowl-like protein building block.

Bibliographic Details
Main Authors: Jiachen Zang, Hai Chen, Xiaorong Zhang, Chenxi Zhang, Jing Guo, Ming Du, Guanghua Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08788-9