The Role of NCOA4-Mediated Ferritinophagy in Health and Disease
Nuclear receptor coactivator 4 (NCOA4) is a selective cargo receptor that mediates the autophagic degradation of ferritin (“ferritinophagy„), the cytosolic iron storage complex. NCOA4-mediated ferritinophagy maintains intracellular iron homeostasis by facilitating ferritin iron s...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/11/4/114 |