Calcium phosphate/thermoresponsive hyaluronan hydrogel composite delivering hydrophilic and hydrophobic drugs

Calcium phosphate/thermoresponsive hyaluronan hydrogel composite delivering hydrophilic and hydrophobic drugs

Background/Objective: Advanced synthetic biomaterials that are able to reduce or replace the need for autologous bone transplantation are still a major clinical need in orthopaedics, dentistry, and trauma. Key requirements for improved bone substitutes are optimal handling properties, ability to fil...

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Bibliographic Details
Main Authors: Dalila Petta, Garland Fussell, Lisa Hughes, Douglas D. Buechter, Christoph M. Sprecher, Mauro Alini, David Eglin, Matteo D'Este
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Orthopaedic Translation
Subjects:
bone graft substitute
composite
drug delivery
thermoresponsive hyaluronan
β-tricalcium phosphate
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X15000856

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http://www.sciencedirect.com/science/article/pii/S2214031X15000856

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