The expression loss of GPIbα due to ectodomain shedding in PRP derived platelet concentrates during storage

Background: Platelet adhesion typically occurs by the critical role of GPIb-V-IX in capturing free-flowing platelets to the injured vessel wall where its rapid binding kinetics enables platelet tethering even under conditions of high shear through the interaction of the major ligand-binding subunit...

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Bibliographic Details
Main Authors: Zeynab Pirmohammad Jamaat, Ehteramolsadat Hosseini, Mehran Ghasemzadeh
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2016-05-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://tumj.tums.ac.ir/browse.php?a_code=A-10-25-5441&slc_lang=en&sid=1