Applying vinpocetine to reverse synaptic ultrastructure by regulating BDNF-related PSD-95 in alleviating schizophrenia-like deficits in rat

Background: Schizophrenia is a mental disorder characterized by hyperlocomotion, cognitive symptoms, and social withdrawal. Brain-derived neurotrophic factor (BDNF) and postsynaptic density (PSD)-95 are related to schizophrenia-like deficits via regulating the synaptic ultrastructure, and play a rol...

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Bibliographic Details
Main Authors: Yue Xu, Chao Deng, Yongqiang Zheng, Nannuan Liu, Beibei Fu
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Comprehensive Psychiatry
Online Access:http://www.sciencedirect.com/science/article/pii/S0010440X19300458