Membrane-Anchored Hairless Protein Restrains Notch Signaling Activity

The Notch signaling pathway governs cell-to-cell communication in higher eukaryotes. In <i>Drosophila</i>, after cleavage of the transmembrane receptor Notch, the intracellular domain of Notch (ICN) binds to the transducer Suppressor of Hairless (Su(H)) and shuttles into the nucleus to a...

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Bibliographic Details
Main Author: Dieter Maier
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/11/1315