Insulin-Like Growth Factor-1 but Not Insulin Predicts Cognitive Decline in Huntington's Disease.

BACKGROUND:Huntington's disease (HD) is one of several neurodegenerative disorders that have been associated with metabolic alterations. Changes in Insulin Growth Factor 1 (IGF-1) and/or insulin input to the brain may underlie or contribute to the progress of neurodegenerative processes. Here,...

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Bibliographic Details
Main Authors: Linda Salem, Nadine Saleh, Gaelle Désaméricq, Katia Youssov, Guillaume Dolbeau, Laurent Cleret, Marie-Laure Bourhis, Jean-Philippe Azulay, Pierre Krystkowiak, Christophe Verny, Françoise Morin, Stéphane Moutereau, French Huntington Study Group, Anne-Catherine Bachoud-Lévi, Patrick Maison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5023180?pdf=render