Integrating data and knowledge to identify functional modules of genes: a multilayer approach

Integrating data and knowledge to identify functional modules of genes: a multilayer approach

Abstract Background Characterizing the modular structure of cellular network is an important way to identify novel genes for targeted therapeutics. This is made possible by the rising of high-throughput technology. Unfortunately, computational methods to identify functional modules were limited by t...

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Bibliographic Details
Main Authors: Lifan Liang, Vicky Chen, Kunju Zhu, Xiaonan Fan, Xinghua Lu, Songjian Lu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
Protein-protein interaction
Graph clustering
Random walk
Multiplex
Topic modeling
Gene expression
Online Access:http://link.springer.com/article/10.1186/s12859-019-2800-y

Internet

http://link.springer.com/article/10.1186/s12859-019-2800-y

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