The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

<p>Abstract</p> <p>Background</p> <p>Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially expressed genes (DEGs) are not reproducible in similar expe...

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Main Authors: Su Zhenqiang, Shippy Richard, Puri Raj K, Peterson Ron L, Mei Nan, Ma Yunqing, Luo Yuling, Li Quan-Zhen, Kawasaki Ernest S, Hong Huixiao, Herman Damir, Han Jing, Guo Xu, Fuscoe James C, Frueh Felix W, Fan Xiao-hui, Collins Patrick J, Chu Tzu-Ming, Bertholet Vincent, Cao Xiaoxi, Bao Wenjun, Barbacioru Catalin C, Amur Shashi, Qian Feng, Fang Hong, Boysen Cecilie, Croner Lisa J, Guo Lei, Goodsaid Federico M, Perkins Roger G, Harris Stephen C, Jensen Roderick V, Jones Wendell D, Shi Leming, Sun Yongming, Sun Hongmei, Thorn Brett, Turpaz Yaron, Wang Charles, Wang Sue, Warrington Janet A, Willey James C, Wu Jie, Xie Qian, Zhang Liang, Zhang Lu, Zhong Sheng, Wolfinger Russell D, Tong Weida
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Bioinformatics