Oxidative stress and cellular pathologies in Parkinson’s disease

Abstract Parkinson’s disease (PD) is a chronic and progressive neurodegeneration of dopamine neurons in the substantia nigra. The reason for the death of these neurons is unclear; however, studies have demonstrated the potential involvement of mitochondria, endoplasmic reticulum, α-synuclein or dopa...

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Bibliographic Details
Main Authors: Lesly Puspita, Sun Young Chung, Jae-won Shim
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-017-0340-9