The renoprotective effect of curcumin against cisplatin-induced acute kidney injury in mice: involvement of miR-181a/PTEN axis

The renoprotective effect of curcumin against cisplatin-induced acute kidney injury in mice: involvement of miR-181a/PTEN axis

Background Nephrotoxicity, especially acute kidney injury (AKI), is the main dose-limiting toxicity of cisplatin. Although recent studies showed that curcumin prevented cisplatin-induced AKI effectively, further studies to understand the mechanism are required. Methods We established an AKI mouse mo...

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Bibliographic Details
Main Authors: Si-Jia Huang, Jing Huang, Yun-Bo Yan, Jiao Qiu, Rui-Qiao Tan, Yu Liu, Qing Tian, Li Guan, Shuai-Shuai Niu, Yanxiang Zhang, Zhijiang Xi, Ying Xiang, Quan Gong
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Renal Failure
Subjects:
curcumin
cisplatin
aki
mir-181a
pten
renoprotective
Online Access:http://dx.doi.org/10.1080/0886022X.2020.1751658

Internet

http://dx.doi.org/10.1080/0886022X.2020.1751658

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