Combination of a Bioceramic Scaffold and Simvastatin Nanoparticles as a Synthetic Alternative to Autologous Bone Grafting

Combination of a Bioceramic Scaffold and Simvastatin Nanoparticles as a Synthetic Alternative to Autologous Bone Grafting

The fragile nature of porous bioceramic substitutes cannot match the toughness of bone, which limits the use of these materials in clinical load-bearing applications. Statins can enhance bone healing, but it could show rhabdomyolysis/inflammatory response after overdosing. In this study, the drug-co...

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Bibliographic Details
Main Authors: Chau-Zen Wang, Yan-Hsiung Wang, Che-Wei Lin, Tien-Ching Lee, Yin-Chih Fu, Mei-Ling Ho, Chih-Kuang Wang
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
combination
bioceramic
nanoparticles
simvastatin
sustained release
scaffold
Online Access:https://www.mdpi.com/1422-0067/19/12/4099

Internet

https://www.mdpi.com/1422-0067/19/12/4099

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