Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis.

We previously identified CCL20 as an early chemokine in the cerebrospinal fluid (CSF) of patients with pneumococcal meningitis but its functional relevance was unknown. Here we studied the role of CCL20 and its receptor CCR6 in pneumococcal meningitis. In a prospective nationwide study, CCL20 levels...

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Bibliographic Details
Main Authors: Matthias Klein, Matthijs C Brouwer, Barbara Angele, Madelijn Geldhoff, Gabriel Marquez, Rosa Varona, Georg Häcker, Helga Schmetzer, Hans Häcker, Sven Hammerschmidt, Arie van der Ende, Hans-Walter Pfister, Diederik van de Beek, Uwe Koedel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3974727?pdf=render