Quantum dots reveal heterogeneous membrane diffusivity and dynamic surface density polarization of dopamine transporter.

The presynaptic dopamine transporter mediates rapid reuptake of synaptic dopamine. Although cell surface DAT trafficking recently emerged as an important component of DAT regulation, it has not been systematically investigated. Here, we apply our single quantum dot (Qdot) tracking approach to monito...

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Bibliographic Details
Main Authors: Oleg Kovtun, Ian D Tomlinson, Riley S Ferguson, Sandra J Rosenthal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225339